Product image is for illustrative purposes only. Actual medication, packaging, and labeling may vary depending on the dispensing pharmacy.
T3/
This capsule combines T4, the thyroid hormone your body stores, with T3, its active form, in one dose. Combination therapy can be an option for some people with hypothyroidism, decided after lab testing and provider review. The quantity is set by your prescription.
- Several delivery forms
- Thyroid support where indicated
- Ongoing monitoring
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Submit your free assessment
Step 1: Complete your medical assessment for review by a licensed medical provider. If appropriate, the provider will determine whether the treatment is right for you.
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Step 2: If approved, your provider selects a formulation, strength, and schedule and explains how to use it. Your order ships in plain, unbranded packaging.
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Step 3: Access your patient portal to communicate with your care team, ask questions, and get support throughout your treatment journey.
T3/T4 Capsule
How T3/T4 supports hormone balance
T3/T4 is a combination capsule containing two thyroid hormones, liothyronine (T3) and levothyroxine (T4). It is available in several strengths, and the dose is titrated per prescription. Hormonal changes affect every woman differently. Your provider reviews your symptoms, history, and goals before recommending whether hormone therapy fits and in what form.
Several delivery forms
Creams, capsules, patches, and a vaginal insert are available through our pharmacy network. Not every option is right for every patient.
Thyroid support where indicated
T3 and T3/T4 capsules are available when your provider determines they are appropriate for you.
Ongoing monitoring
Your provider follows up to check how you are responding and adjusts your plan as needed over time.
Provider-guided from start to finish
A licensed provider reviews your health history, checks for contraindications, sets an appropriate starting plan, and monitors your progress over time.
How to use it
Clear instructions for your prescribed formulation arrive with your first order.
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Your treatment is evaluated by qualified, licensed providers.
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Medication is prescribed only when clinically appropriate.
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Quality and ingredient standards
Made in the U.S.A.
Some treatments are compounded by licensed U.S. pharmacies in facilities registered with the FDA. Registration does not mean a compounded medication is an FDA-approved finished medication.
USP <797>
Sterile compounding standards.
Documented handling.
Every batch released to spec.
ISO Class 7
Cleanroom-grade air.
Filtered environments.
Tighter contamination control.
Clean ingredients, careful delivery
- No heavy metals
- No added dyes
- Licensed U.S. pharmacies
- Provider-prescribed
- Cold-chain protection
- Plain, unbranded packaging
- Serves all 50 states
- HSA and FSA eligible
Medication guide
What to know about T3/T4 Capsule
General education to help you prepare for a conversation with a licensed provider. It is not a prescription or personal medical advice.
- Generic name
- Liothyronine (T3) and levothyroxine (T4)
- Brand names
- Armour Thyroid and NP Thyroid are animal-derived T3/T4 products (not FDA-approved); none is a compounded synthetic combination
- Drug class
- Thyroid hormone
- Form
- Combination capsule
- Regulatory status
- Compounded, not FDA-approved
This compounded capsule combines synthetic T3 and T4. It is not FDA-approved. Levothyroxine and liothyronine are each FDA-approved separately. Thyroid hormone labels carry a boxed warning against use for weight loss.
Compounded medications are not FDA-approved. FDA does not review them for safety, effectiveness or quality before they are dispensed. A compounded preparation can differ from approved products in strength, ingredients, dosage form and how it is absorbed, so it should not be assumed to work the same way as an approved medication. Compounding is meant for patients whose needs cannot be met by an FDA-approved drug.
Overview
A single capsule containing both thyroid hormones, used by some providers for hypothyroidism when symptoms persist on T4 alone.
Who may be evaluated for it
- People with hypothyroidism confirmed by blood tests, usually already treated with levothyroxine.
Who may not be a good fit
- Anyone without a diagnosed thyroid condition, including for weight loss or fatigue alone.
- People with untreated adrenal insufficiency.
- People with an overactive thyroid, recent heart attack or uncontrolled heart rhythm problems need caution.
How it works
T3 is the active form of thyroid hormone. It enters cells and switches on genes that control metabolism, heart rate, temperature and energy use. Most T3 in the body is normally converted from T4.
What is still uncertain
Whether some people benefit from added T3 because of how they convert T4 to T3 is still being researched.
Potential benefits and realistic timelines
What the evidence supports
- Thyroid hormone replacement corrects hypothyroidism.
Early or limited research
- Some patients report feeling better on T4 plus T3, but most trials have not shown a consistent advantage over T4 alone.
Not established
- Weight loss in people with normal thyroid function (and it can be dangerous).
- Advantages of sustained-release capsules over standard tablets.
- DaysT3 acts within hours to days.
- 4 to 8 weeksThyroid labs are rechecked after starting or changing the dose.
Results vary from person to person. Your provider decides whether and how long to continue.
How it’s used
- Take at the same time each day, consistently with or without food.
- Separate from calcium, iron, antacids and bile-acid binders by at least 4 hours.
If you miss a dose
Take it when you remember unless it is near your next dose. Do not double up.
Storage and handling
Room temperature, away from light and moisture.
Your prescription label and provider instructions always take priority over this general information. Do not change your dose or stop without talking to your provider.
Side effects and safety
More common, usually manageable
- Symptoms of too much thyroid hormone: palpitations, nervousness, sweating, heat intolerance, trouble sleeping
Less common but serious
- Irregular heart rhythm (especially atrial fibrillation)
- Chest pain in people with heart disease
- Bone loss with long-term overtreatment
Get medical help right away
- Chest pain, a racing or irregular heartbeat, or fainting
Call 911 or go to the nearest emergency room for chest pain, trouble breathing, swelling of the face or throat, fainting, or signs of a stroke (sudden weakness, numbness, trouble speaking or seeing).
Pregnancy, breastfeeding and fertility
Thyroid needs usually rise in pregnancy. Tell your provider right away if you become pregnant; levothyroxine is usually preferred.
Interactions and combinations
Known interactions
- Calcium, iron, antacids and cholestyramine reduce absorption.
- Warfarin: thyroid hormone increases its effect.
- Diabetes medications: doses may need adjusting.
- Oral estrogen can raise thyroid hormone needs.
Related treatments and options
Listed for education, not as a recommendation to combine. Any combination needs your provider’s approval.
- Liothyronine (T3) SRAvoid
Already contains T3.
- LevothyroxineAvoid
Already contains T4 unless your provider directs otherwise.
Monitoring and follow-up
- TSH and free T3/free T4 4 to 8 weeks after starting or any dose change, then periodically.
- Heart rate and symptom review, especially in older adults or people with heart disease.
Lab tests and follow-up visits are not included in the medication price unless your plan says so. Your provider will tell you what is needed.
Alternatives to discuss
- Levothyroxine (T4)
Standard first-line FDA-approved treatment.
- Liothyronine (T3) SR
T3 alone, usually added to separate T4.
Lab tested medications for quality and potency.
Every medication ships from a licensed U.S. pharmacy in our network, delivered straight to your door.
Third party quality control testing
Compounded in U.S. pharmacies
Dosage, Schedule & Supply
- Dosage
- Available in several T3/T4 strengths, titrated per prescription.
- Schedule
- Determined by your prescribing provider.
- Supply
- Quantity set by your prescription.
- Estimated Supply Duration
- Varies based on the quantity and schedule on your prescription.
Supply duration is an estimate based on the prescribed treatment plan. Actual duration may vary depending on dosage, frequency of use, and medication expiration.
Treatment information is for educational purposes. Your licensed healthcare provider will determine the appropriate dosage and schedule. Always follow your prescription instructions.
Frequently Asked Questions
How is this different from Armour Thyroid?
Armour Thyroid is made from pig thyroid gland. This capsule is a compounded mix of synthetic T3 and T4. Neither is FDA-approved.
Can thyroid hormone help me lose weight?
No. Labels carry a boxed warning against using thyroid hormone for weight loss in people with normal thyroid function; doses large enough to cause weight loss can cause serious harm.
Why would T3 be added?
Some people with hypothyroidism still have symptoms on T4 alone. Adding T3 is an option some providers try, though trials have shown mixed results.
Why separate it from calcium or iron?
They bind thyroid hormone in the gut and reduce how much you absorb.
Do I need a prescription?
Yes. After your free consultation, a licensed provider reviews your intake, symptoms, and health history to decide what’s appropriate for you.
Is every formulation appropriate for me?
No. Your provider selects a formulation based on your individual symptoms, history, and goals, not every option listed is appropriate for every patient.
Is this available in my state?
Availability varies by formulation and state. Your provider will confirm what can be prescribed and shipped to you during your consultation.
Can I use my HSA or FSA?
Yes. Medura accepts HSA and FSA cards at checkout, and we can provide documentation for reimbursement if you need it.
What happens after I request treatment through Medura?
You complete an online assessment about your health history, current medications and goals. A licensed provider reviews it and decides whether a prescription is appropriate. Completing the assessment does not guarantee a prescription. If one is written, a licensed pharmacy prepares and ships it, and your provider can adjust or stop treatment as needed. If lab work is needed, your provider will tell you; it may be ordered and billed separately.
What to expect and possible side effects
- 1
Start with a consultation
A licensed provider reviews your intake, symptoms, and health history to determine whether hormone therapy is appropriate and which formulation may fit.
- 2
A plan matched to you
If approved, your provider selects a formulation, strength, and schedule, and explains how to use it.
- 3
Ongoing monitoring
Your provider follows up to check how you are responding and adjusts your plan as needed over time.
Questions to ask your provider
- 1.Do my labs show I need T3, not just T4?
- 2.Why SR capsules instead of standard tablets?
- 3.When will my labs be rechecked?
- 4.Is my heart healthy enough for T3?
References
- Liothyronine sodium tablets prescribing information (DailyMed)(opens in a new tab)
- Hypothyroidism (NIDDK)(opens in a new tab)
- Compounding and the FDA: Questions and Answers (FDA)(opens in a new tab)
Sources last checked October 17, 2026. This page is for general education and does not replace advice from a licensed provider. Treatment requires a clinical evaluation, and a prescription is written only if a provider decides it is appropriate. Individual results vary.
Related Products & Treatments
Explore other options that may support your goals.
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BIEST/Progesterone CapsuleA combination capsule of BIEST and immediate-release progesterone. Helps relieve menopause symptoms such as hot flashes and night sweats, with progesterone for balance.View details for BIEST/Progesterone Capsule
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Estradiol CapsuleSingle-ingredient oral estradiol capsules at 1–2 mg. Helps relieve menopause symptoms such as hot flashes and night sweats.View details for Estradiol Capsule
Estradiol PatchA transdermal estradiol patch at 0.025–0.1 mg/day, 8-pack. Helps relieve menopause symptoms such as hot flashes and night sweats.View details for Estradiol Patch
Estradiol Vaginal InsertA 10 mcg estradiol vaginal insert. Helps relieve vaginal dryness and discomfort during menopause.View details for Estradiol Vaginal Insert
Progesterone CapsuleImmediate-release progesterone capsules in several strengths. Helps support sleep and hormone balance, and protects the uterine lining for those taking estrogen.View details for Progesterone Capsule
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