Medura PT-141 Injectable vial in premium metallic navy packaging

Product image is for illustrative purposes only. Actual medication, packaging, and labeling may vary depending on the dispensing pharmacy.

Sexual Health

PT-141 Injectable

PT-141 (bremelanotide) works on the brain's desire pathways rather than on blood flow, which sets it apart from ED tablets. The brand-name form is FDA-approved for low sexual desire in premenopausal women; this compounded version and other uses are off-label. Used as needed and supplied as one 5 mL vial.

  • Daily and as-needed options
  • A provider who listens
  • Discreet delivery

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Know what's included in your treatment, from your initial virtual consultation to prescription delivery.

  • Your Prescription MedicationYour prescribed medication is priced as listed on its treatment page, with no additional medication markup at checkout. Injectable treatments also include essential supplies at no extra cost: alcohol prep pads, gauze pads, syringes, drawing and injection needles, plus clear administration instructions.
  • Initial Virtual ConsultationYour required initial virtual consultation is included in the treatment price. Refills during its validity period are not charged that fee again.
  • Licensed Provider ReviewA licensed provider reviews your information to decide if treatment is appropriate. An assessment does not guarantee a prescription.
  • Unlimited Doctor AccessIncludes unlimited doctor access in-between subscriptions.
  • Free Expedited Prescription ShippingIncluded with eligible prescription orders, shipped in discreet, unbranded packaging.
  • Temperature-Controlled PackagingCold-pack packaging is included when your medication requires it.
  • One Transparent Price. Everything Included.The price displayed isn't just for your medication. It also covers the required initial consultation with a licensed doctor, eligible expedited shipping, supplies, and temperature-controlled packaging when needed. While each of these services carries its own cost, we've bundled them into one reasonable, upfront price.

How it works

  1. Submit your free assessment

    Step 1: Complete your medical assessment for review by a licensed medical provider. If appropriate, the provider will determine whether the treatment is right for you.

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  2. Get your plan and your order at home

    Step 2: If approved, your provider selects a formulation and explains how and when to use it. Orders ship in plain, unbranded packaging.

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  3. Receive 24/7 Support and Ongoing Care

    Step 3: Access your patient portal to communicate with your care team, ask questions, and get support throughout your treatment journey.

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PT-141 Injectable

How PT-141 supports sexual wellness

PT-141, also called bremelanotide, is an injectable peptide. The PT-141 Starter presentation is one 5 mL vial at 10 mg/mL, used as needed (PRN). Sexual health concerns are common and deserve a judgment-free path to care. Your consultation is confidential and your order ships discreetly.

  • Daily and as-needed options

    Tadalafil, Sildenafil, PT-141, and compounded troches are available through our pharmacy network in daily and as-needed formats.

  • A provider who listens

    A licensed provider reviews your intake and health history privately and explains which option, if any, fits your needs.

  • Discreet delivery

    Orders ship in plain, unbranded packaging with no pharmacy name on the outside.

  • Provider-guided from start to finish

    A licensed provider reviews your health history, checks for contraindications, sets an appropriate starting plan, and monitors your progress over time.

  • How to use it

    Clear instructions for your specific formulation arrive with your first order.

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Real Medical Professionals. Personalized Care. Transparent Pricing.

Your health deserves more than a one-size-fits-all approach.

Medura connects you with licensed medical professionals who take the time to review your health history, evaluate your individual needs, and determine which treatments may be right for you.

We believe quality healthcare should come with professional oversight, personalized attention, and honest, transparent medication pricing.

No unnecessary medication markups. No confusing treatment pricing. Just a more straightforward approach to getting the care you deserve.

  • Licensed Medical Professionals

    Your treatment is evaluated by qualified, licensed providers.

  • Personalized Medical Evaluations

    Recommendations are based on your individual health needs.

  • Provider-Approved Prescriptions

    Medication is prescribed only when clinically appropriate.

  • Transparent Medication Pricing

    Know the medication price before moving forward.

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Connect with a licensed medical professional and discover whether treatment is right for you. Prescriptions require a medical evaluation and provider approval.

Every dose, made simple.

Daily or as needed, depending on your plan. We explain exactly how and when to use your prescription so it fits naturally into your life.

  • Step-by-step guidance

    Clear instructions for your specific formulation arrive with your first order.

  • A dose that fits you

    Your provider sets your starting dose and adjusts it over time based on how you respond.

  • Support between doses

    Have a question along the way? The Medura care team is here to help you stay on track.

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PT-141 Injectable available now

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Quality and ingredient standards

Made in the U.S.A.

Some treatments are compounded by licensed U.S. pharmacies in facilities registered with the FDA. Registration does not mean a compounded medication is an FDA-approved finished medication.

  • USP <797>

    Sterile compounding standards.

    Documented handling.

    Every batch released to spec.

  • ISO Class 7

    Cleanroom-grade air.

    Filtered environments.

    Tighter contamination control.

Clean ingredients, careful delivery

  • No heavy metals
  • No added dyes
  • Licensed U.S. pharmacies
  • Provider-prescribed
  • Cold-chain protection
  • Plain, unbranded packaging
  • Serves all 50 states
  • HSA and FSA eligible

Medication guide

What to know about PT-141 Injectable

General education to help you prepare for a conversation with a licensed provider. It is not a prescription or personal medical advice.

Generic name
Bremelanotide (PT-141)
Brand names
Vyleesi (FDA-approved autoinjector)
Drug class
Melanocortin receptor agonist
Form
Injection under the skin as needed
Regulatory status
Compounded, not FDA-approved
FDA-approved use
Vyleesi: acquired, generalized HSDD in premenopausal women not caused by a medical or psychiatric condition, relationship problems or medications.

Bremelanotide is FDA-approved as Vyleesi, a 1.75 mg autoinjector for premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD). A compounded vial is not FDA-approved. Use in men or postmenopausal women is off-label.

Compounded medications are not FDA-approved. FDA does not review them for safety, effectiveness or quality before they are dispensed. A compounded preparation can differ from approved products in strength, ingredients, dosage form and how it is absorbed, so it should not be assumed to work the same way as an approved medication. Compounding is meant for patients whose needs cannot be met by an FDA-approved drug.

Overview

Bremelanotide is used to address low sexual desire that causes distress. It works in the brain rather than on blood flow.

Who may be evaluated for it

  • Premenopausal women with low sexual desire that causes distress and is not explained by another condition (the approved use).

Who may not be a good fit

  • People with uncontrolled high blood pressure or known heart disease.
  • Anyone who is pregnant.
  • People taking oral naltrexone for alcohol or opioid use.

How it works

Bremelanotide activates melanocortin receptors (mainly MC4R) in the brain, which are involved in sexual desire and arousal. It does not act on blood flow the way ED pills do.

What is still uncertain

Exactly how melanocortin activation increases desire is not fully understood.

Potential benefits and realistic timelines

What the evidence supports

  • In trials of Vyleesi, premenopausal women with HSDD reported a modest increase in desire and less distress compared with placebo.

Not established

  • Effectiveness in men or postmenopausal women.
  • That compounded bremelanotide performs like Vyleesi.
  1. About 45 minutesVyleesi is injected at least 45 minutes before anticipated sexual activity.
  2. 8 weeksThe label advises stopping if there is no improvement after 8 weeks.

Results vary from person to person. Your provider decides whether and how long to continue.

How it’s used

Vyleesi label: 1.75 mg under the skin at least 45 minutes before sex; no more than 1 dose in 24 hours and no more than 8 doses a month.

  • Inject under the skin of the abdomen or thigh as directed.
  • Use a new sterile needle each time.

If you miss a dose

Used as needed, so there is no missed dose. Never exceed 1 dose in 24 hours.

Storage and handling

Store as directed on the pharmacy label; compounded vials are often refrigerated after opening.

Your prescription label and provider instructions always take priority over this general information. Do not change your dose or stop without talking to your provider.

Side effects and safety

More common, usually manageable

  • Nausea (very common, especially with the first dose)
  • Flushing
  • Headache
  • Injection-site reactions

Less common but serious

  • Temporary rise in blood pressure and drop in heart rate after each dose
  • Darkening of the skin, gums or breasts (focal hyperpigmentation), especially with frequent use; may not go away

Get medical help right away

  • Severe headache, chest pain or palpitations after a dose
  • Persistent vomiting

Call 911 or go to the nearest emergency room for chest pain, trouble breathing, swelling of the face or throat, fainting, or signs of a stroke (sudden weakness, numbness, trouble speaking or seeing).

Pregnancy, breastfeeding and fertility

Stop if pregnant. Use effective birth control while using it.

Interactions and combinations

Known interactions

  • Oral naltrexone: bremelanotide can greatly lower naltrexone levels, which may make it fail.
  • Medicines that need steady absorption (such as some antibiotics) may be affected by slowed stomach emptying.

Related treatments and options

Listed for education, not as a recommendation to combine. Any combination needs your provider’s approval.

Monitoring and follow-up

  • Blood pressure review before starting.
  • Check-in after about 8 weeks to judge benefit.
  • Watch for skin darkening.

Lab tests and follow-up visits are not included in the medication price unless your plan says so. Your provider will tell you what is needed.

Alternatives to discuss

  • Flibanserin (Addyi)

    A daily oral FDA-approved treatment for HSDD in premenopausal women.

  • Fem Max Troche

    A compounded combination containing PT-141; not FDA-approved.

  • Counseling or sex therapy

    Often recommended as a first step for low desire.

Potency TestTested
Sterility TestTested
Endotoxin TestTested
pH TestTested

Lab tested medications for quality and potency.

Every medication ships from a licensed U.S. pharmacy in our network, delivered straight to your door.

  • Third party quality control testing

  • Compounded in U.S. pharmacies

Dosage, Schedule & Supply

Dosage
10 mg/mL concentration.
Schedule
As needed, as directed by your provider.
Supply
One 5 mL vial.
Estimated Supply Duration
Varies depending on how often the medication is used.

Supply duration is an estimate based on the prescribed treatment plan. Actual duration may vary depending on dosage, frequency of use, and medication expiration.

Treatment information is for educational purposes. Your licensed healthcare provider will determine the appropriate dosage and schedule. Always follow your prescription instructions.

Frequently Asked Questions

Is PT-141 the same as Vyleesi?

Same active ingredient, but compounded PT-141 is not FDA-approved and has not been tested like Vyleesi.

Why do I feel nauseated?

Nausea is the most common side effect, especially at first. Tell your provider if it is severe.

Does it work for men?

It is only approved for premenopausal women. Use in men is off-label and evidence is limited.

Do I need a prescription?

Yes. After your free, confidential consultation, a licensed provider reviews your intake and health history to decide what’s appropriate for you.

Is this confidential?

Yes. Your consultation is private, and orders ship in plain, unbranded packaging with no pharmacy name on the outside.

Can I use my HSA or FSA?

Yes. Medura accepts HSA and FSA cards at checkout, and we can provide documentation for reimbursement if you need it.

What happens after I request treatment through Medura?

You complete an online assessment about your health history, current medications and goals. A licensed provider reviews it and decides whether a prescription is appropriate. Completing the assessment does not guarantee a prescription. If one is written, a licensed pharmacy prepares and ships it, and your provider can adjust or stop treatment as needed. If lab work is needed, your provider will tell you; it may be ordered and billed separately.

What to expect and possible side effects

  1. 1

    Start with a confidential consultation

    A licensed provider reviews your intake and health history in a private setting to understand your concern and goals.

  2. 2

    A discreet plan

    If approved, your provider selects a formulation and explains how and when to use it. Orders ship in plain, unbranded packaging.

  3. 3

    Ongoing support

    Your provider is available to adjust your plan if your needs change.

Common side effects:

  • Nausea (most common, typically temporary)
  • Flushing or warmth in the face and neck
  • Headache
  • Mild increase in blood pressure (monitored during consultation)
  • Injection site discomfort

Important Safety Information

This treatment is prescription-only. Your eligibility will be determined during your free consultation with a provider based on your full medical history, current medications, and health goals. Nothing on this page guarantees approval.

Generally appropriate for

  • Adult women experiencing low sexual desire or hypoactive sexual desire disorder
  • Those who have not responded to hormonal interventions
  • Patients without significant cardiovascular conditions

Generally not appropriate if

  • Patients with uncontrolled hypertension
  • Those taking certain medications that interact with melanocortin agonists
  • Pregnant or breastfeeding individuals
  • Patients with a history of cardiovascular disease without provider clearance

Common side effects

  • Nausea (most common, typically temporary)
  • Flushing or warmth in the face and neck
  • Headache
  • Mild increase in blood pressure (monitored during consultation)
  • Injection site discomfort

Individual results vary. This is not a complete list of potential side effects. Your provider will review all risks during your consultation.

Questions to ask your provider

  1. 1.Is my low desire likely to respond to bremelanotide?
  2. 2.Is my blood pressure safe for it?
  3. 3.What should I do about nausea?
  4. 4.How long should I try it before deciding?

References

Sources last checked October 17, 2026. This page is for general education and does not replace advice from a licensed provider. Treatment requires a clinical evaluation, and a prescription is written only if a provider decides it is appropriate. Individual results vary.

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Educational only. Not medical advice.