Medura NAD+ Nasal Spray bottle in premium metallic navy packaging

Product image is for illustrative purposes only. Actual medication, packaging, and labeling may vary depending on the dispensing pharmacy.

Longevity & Anti-Aging

NAD+ Nasal Spray

NAD+ nasal spray offers a quick, needle-free way to add this cellular-energy coenzyme to a provider-guided wellness routine. It is a compounded preparation, and research on its benefits is still emerging. Supplied at 300 mg/mL in 15 mL containers, with the number set by your prescription.

  • Energy metabolism
  • Cellular repair
  • Healthy aging support

Save 10% on Your First Prescription Order

New prescription customers save 10% with code MEDURA10. Enter your code during checkout after your assessment.

Answer to see the price

Which one of the following best describes your preferences today?

Your Treatment. Everything Included.

Know what's included in your treatment, from your initial virtual consultation to prescription delivery.

  • Your Prescription MedicationYour prescribed medication is priced as listed on its treatment page, with no additional medication markup at checkout. Injectable treatments also include essential supplies at no extra cost: alcohol prep pads, gauze pads, syringes, drawing and injection needles, plus clear administration instructions.
  • Initial Virtual ConsultationYour required initial virtual consultation is included in the treatment price. Refills during its validity period are not charged that fee again.
  • Licensed Provider ReviewA licensed provider reviews your information to decide if treatment is appropriate. An assessment does not guarantee a prescription.
  • Unlimited Doctor AccessIncludes unlimited doctor access in-between subscriptions.
  • Free Expedited Prescription ShippingIncluded with eligible prescription orders, shipped in discreet, unbranded packaging.
  • Temperature-Controlled PackagingCold-pack packaging is included when your medication requires it.
  • One Transparent Price. Everything Included.The price displayed isn't just for your medication. It also covers the required initial consultation with a licensed doctor, eligible expedited shipping, supplies, and temperature-controlled packaging when needed. While each of these services carries its own cost, we've bundled them into one reasonable, upfront price.

How it works

  1. Submit your free assessment

    Step 1: Complete your medical assessment for review by a licensed medical provider. If appropriate, the provider will determine whether the treatment is right for you.

    Hands holding a phone that shows a short health questionnaire

  2. Get your plan and your order at home

    Step 2: Once approved, your provider sets a schedule that fits your routine. Your order ships in plain, unbranded packaging. Temperature-sensitive items ship with cold-chain protection.

    A sealed, plain shipping box

  3. Receive 24/7 Support and Ongoing Care

    Step 3: Access your patient portal to communicate with your care team, ask questions, and get support throughout your treatment journey.

    A smiling woman reading a message on her phone
A cheerful South Asian woman working creatively near a sunny window

NAD+ Nasal Spray

How NAD+ Nasal supports energy and recovery

NAD+ is a coenzyme your cells use to turn food into usable energy and to carry out everyday repair. Levels naturally decline with age, and NAD+ therapy is studied for its role in supporting that underlying machinery. NAD+ sits at the center of how your cells produce energy and maintain themselves. The nasal spray offers a needle-free way to take it. Here is what it is studied for and how it may support the way you feel day to day.

  • Energy metabolism

    NAD+ helps your cells convert food into the energy that powers everything you do. Supporting healthy NAD+ levels is studied for its role in steady, usable energy.

  • Cellular repair

    Your cells rely on NAD+ to run their repair and maintenance processes. NAD+ therapy is studied for how it may support this ongoing upkeep as you age.

  • Healthy aging support

    Because NAD+ levels decline over time, replenishing them is an active area of longevity research. NAD+ may support the cellular resilience that helps you keep doing what you love.

  • Provider-guided from start to finish

    A licensed provider reviews your health history, checks for contraindications, sets an appropriate starting plan, and monitors your progress over time.

  • How to use it

    Clear instructions show you how to use your NAD+ nasal spray, starting with your very first dose.

Start my free assessment
A physician smiling and listening to a patient during a consultation

Real Medical Professionals. Personalized Care. Transparent Pricing.

Your health deserves more than a one-size-fits-all approach.

Medura connects you with licensed medical professionals who take the time to review your health history, evaluate your individual needs, and determine which treatments may be right for you.

We believe quality healthcare should come with professional oversight, personalized attention, and honest, transparent medication pricing.

No unnecessary medication markups. No confusing treatment pricing. Just a more straightforward approach to getting the care you deserve.

  • Licensed Medical Professionals

    Your treatment is evaluated by qualified, licensed providers.

  • Personalized Medical Evaluations

    Recommendations are based on your individual health needs.

  • Provider-Approved Prescriptions

    Medication is prescribed only when clinically appropriate.

  • Transparent Medication Pricing

    Know the medication price before moving forward.

Start My Free Assessment

Connect with a licensed medical professional and discover whether treatment is right for you. Prescriptions require a medical evaluation and provider approval.

Quality and ingredient standards

Made in the U.S.A.

Some treatments are compounded by licensed U.S. pharmacies in facilities registered with the FDA. Registration does not mean a compounded medication is an FDA-approved finished medication.

  • USP <797>

    Sterile compounding standards.

    Documented handling.

    Every batch released to spec.

  • ISO Class 7

    Cleanroom-grade air.

    Filtered environments.

    Tighter contamination control.

Clean ingredients, careful delivery

  • No heavy metals
  • No added dyes
  • Licensed U.S. pharmacies
  • Provider-prescribed
  • Cold-chain protection
  • Plain, unbranded packaging
  • Serves all 50 states
  • HSA and FSA eligible

Medication guide

What to know about NAD+ Nasal Spray

General education to help you prepare for a conversation with a licensed provider. It is not a prescription or personal medical advice.

Generic name
Nicotinamide adenine dinucleotide (NAD+)
Drug class
Coenzyme (vitamin B3-derived molecule)
Form
Nasal spray
Regulatory status
Not FDA-approved for any use

NAD+ is not FDA-approved to treat or prevent any condition, in any form. Nasal NAD+ is a compounded preparation whose safety, effectiveness and quality have not been reviewed by FDA.

Compounded medications are not FDA-approved. FDA does not review them for safety, effectiveness or quality before they are dispensed. A compounded preparation can differ from approved products in strength, ingredients, dosage form and how it is absorbed, so it should not be assumed to work the same way as an approved medication. Compounding is meant for patients whose needs cannot be met by an FDA-approved drug.

Overview

NAD+ is offered by some providers as a wellness therapy. Claims about energy, aging or recovery are not supported by strong clinical evidence.

Who may be evaluated for it

  • Adults interested in NAD+ who understand that its benefits are unproven and want provider oversight.

Who may not be a good fit

  • People who are pregnant or breastfeeding (not studied).
  • People with active cancer should discuss first: NAD+ supports cell metabolism generally, and effects on tumors are not known.
  • Anyone expecting a treatment for a diagnosed condition.

How it works

NAD+ is a molecule every cell uses to turn food into energy and to repair DNA. Levels decline with age in animal and some human studies.

A nasal spray delivers NAD+ through the lining of the nose without a needle. How much is absorbed, and whether it meaningfully raises levels inside cells, is unclear.

What is still uncertain

How much sprayed NAD+ is absorbed intact, and whether raising it changes health outcomes in people, is not established.

Potential benefits and realistic timelines

No clinical benefit has been established in well-designed human trials for this use.

Early or limited research

  • Animal studies link higher NAD+ to better metabolic health. Small human studies of oral precursors (NR, NMN) show they raise blood NAD+ levels, with mixed effects on health measures.

Not established

  • Anti-aging effects or longer life in people.
  • Improved energy, focus, athletic performance or addiction recovery.
  • Benefits of nasal NAD+ specifically.
  1. Not establishedThere is no reliable evidence on when, or whether, people notice benefits. Your provider will check in on how you feel and on side effects.

Results vary from person to person. Your provider decides whether and how long to continue.

How it’s used

  • Use exactly as written on your pharmacy label.
  • Prime the pump as directed and use the spray in each nostril as your provider instructs.
  • Do not share your spray bottle.

If you miss a dose

No official guidance exists. Resume your usual schedule; do not double up.

Storage and handling

Usually refrigerated; follow the label and beyond-use date.

Your prescription label and provider instructions always take priority over this general information. Do not change your dose or stop without talking to your provider.

Side effects and safety

More common, usually manageable

  • Nasal irritation, dryness or stinging
  • Flushing or warmth
  • Nausea
  • Headache

Less common but serious

  • Allergic reaction

Get medical help right away

  • Chest pain or trouble breathing that does not pass quickly

Call 911 or go to the nearest emergency room for chest pain, trouble breathing, swelling of the face or throat, fainting, or signs of a stroke (sudden weakness, numbness, trouble speaking or seeing).

Pregnancy, breastfeeding and fertility

Not studied in pregnancy or breastfeeding; not recommended.

Interactions and combinations

Known interactions

  • No well-documented drug interactions. Tell your provider about supplements such as niacin, NR or NMN.

Related treatments and options

Listed for education, not as a recommendation to combine. Any combination needs your provider’s approval.

  • SermorelinEvidence insufficient

    Sometimes offered together; no evidence of combined benefit.

  • NR or NMN supplementsEvidence insufficient

    Overlapping purpose; no evidence for combining.

Monitoring and follow-up

  • Review of goals, other supplements and medical history.
  • Check-in on side effects and whether you perceive any benefit.

Lab tests and follow-up visits are not included in the medication price unless your plan says so. Your provider will tell you what is needed.

Alternatives to discuss

  • NAD+ Injection

    Given under the skin on a set schedule; compounded.

  • Sleep, exercise and nutrition

    Exercise in particular raises NAD+ in muscle and has strong evidence for healthy aging.

  • Glutathione

    Another wellness injection; also unproven.

Potency TestTested
Sterility TestTested
Endotoxin TestTested
pH TestTested

Lab tested medications for quality and potency.

Every medication ships from a licensed U.S. pharmacy in our network, delivered straight to your door.

  • Third party quality control testing

  • Compounded in U.S. pharmacies

Dosage, Schedule & Supply

Dosage
300 mg/mL concentration.
Schedule
Determined by your prescribing provider.
Supply
15 mL containers. The number per supply is set by your prescription.
Estimated Supply Duration
Varies based on the number of sprays prescribed and how often they are used.

Supply duration is an estimate based on the prescribed treatment plan. Actual duration may vary depending on dosage, frequency of use, and medication expiration.

Treatment information is for educational purposes. Your licensed healthcare provider will determine the appropriate dosage and schedule. Always follow your prescription instructions.

Frequently Asked Questions

Do I need a prescription?

Yes. After your free consultation, a licensed provider reviews your intake and health history to decide whether this treatment is right for you.

What is in my NAD+ Nasal Spray supply?

NAD+ Nasal Spray is supplied at 300 mg/mL. Your provider confirms the dose and how long a supply lasts for your plan.

How is NAD+ Nasal Spray used?

It is a needle-free spray used in each nostril, usually as a simple daily routine. Your provider confirms the schedule for your plan.

How is this different from the NAD+ Injection?

Both deliver NAD+ and both require a prescription. The nasal spray is needle-free and used as a simple daily routine, while the injection is given under the skin on a set schedule. Your provider helps decide which format fits you.

How soon will I notice a difference?

NAD+ works gradually. Many patients focus on steady energy and recovery over the first weeks and months. Individual experiences vary.

What are the common side effects?

Effects are usually mild and brief, such as flushing or warmth after a dose, mild nausea, headache, or irritation from the nasal spray. Your provider reviews the risks with you during your consultation.

What if a provider decides this isn't right for me?

Your consultation is free, and no payment is needed to complete the assessment. If a provider decides this treatment isn't appropriate for you, they will explain why and may suggest other options.

How much does it cost?

The consultation is free and you pay nothing to complete the assessment. If a provider approves treatment, you see the exact monthly price for your plan before you are charged. There are no surprise fees.

Can I use my HSA or FSA?

Yes. Medura accepts HSA and FSA cards at checkout, and we can provide documentation for reimbursement if you need it.

How is it shipped?

Your treatment arrives in plain, unbranded packaging with no pharmacy name on the outside. Temperature-sensitive items ship with cold-chain protection.

What happens after I request treatment through Medura?

You complete an online assessment about your health history, current medications and goals. A licensed provider reviews it and decides whether a prescription is appropriate. Completing the assessment does not guarantee a prescription. If one is written, a licensed pharmacy prepares and ships it, and your provider can adjust or stop treatment as needed. If lab work is needed, your provider will tell you; it may be ordered and billed separately.

What to expect and possible side effects

  1. 1

    Start with a consultation

    You complete a short intake and a licensed provider reviews your health history to decide whether NAD+ Nasal Spray is right for you.

  2. 2

    A simple at-home routine

    Once approved, your plan follows an easy routine you can keep at home, usually a simple daily spray in each nostril as your provider directs.

  3. 3

    What to expect

    NAD+ works gradually. Many patients focus on steady energy and recovery over the first weeks and months. Individual experiences vary.

Common side effects:

  • Flushing or warmth after a dose (common, typically brief)
  • Mild nausea or stomach discomfort during or shortly after a dose
  • Headache or lightheadedness
  • Nasal irritation, dryness or stinging
  • Fatigue immediately following a dose (uncommon, resolves within hours)

Important Safety Information

This treatment is prescription-only. Your eligibility will be determined during your free consultation with a provider based on your full medical history, current medications, and health goals. Nothing on this page guarantees approval.

Generally appropriate for

  • Adults seeking support for cellular energy, mental clarity, or healthy aging
  • Those experiencing fatigue, brain fog, or age-related decline in vitality
  • Patients interested in longevity-focused, provider-supervised care
  • Adults without contraindications to nasal spray treatments

Generally not appropriate if

  • Patients with active cancer or currently undergoing chemotherapy without oncologist clearance
  • Those with known hypersensitivity to NAD+ or niacinamide-related compounds
  • Pregnant or breastfeeding individuals without medical supervision
  • Patients with severe kidney or liver impairment without prior provider evaluation

Common side effects

  • Flushing or warmth after a dose (common, typically brief)
  • Mild nausea or stomach discomfort during or shortly after a dose
  • Headache or lightheadedness
  • Nasal irritation, dryness or stinging
  • Fatigue immediately following a dose (uncommon, resolves within hours)

Individual results vary. This is not a complete list of potential side effects. Your provider will review all risks during your consultation.

Questions to ask your provider

  1. 1.What evidence supports NAD+ for my goals?
  2. 2.Nasal spray or injection: what are the trade-offs?
  3. 3.How will we decide if it is worth continuing?
  4. 4.Are there risks given my health history?

References

Sources last checked October 17, 2026. This page is for general education and does not replace advice from a licensed provider. Treatment requires a clinical evaluation, and a prescription is written only if a provider decides it is appropriate. Individual results vary.

Related Products & Treatments

Explore other options that may support your goals.

Not Sure Where to Start?

We're here to make things simple. Book a free 15-minute Google Meet consultation with our team to get help navigating Medura, understanding the assessment process, pricing, and next steps.

Book a Free 15-Minute Consultation

This is a customer support session on Google Meet, not a medical consultation. You will not receive medical care, medical advice, or treatment recommendations, and you will not be speaking with a licensed physician. All medical evaluations and treatment decisions are handled separately by licensed healthcare providers.

Map of the United States with every state highlighted

Health and wellness, nationwide.

From everyday wellness essentials to personalized medical treatments, Medura makes it easier to take control of your health, wherever you are in the U.S.

Explore personalized treatment guidance
Health quiz

Not sure where to start?

Answer 10 quick questions to explore Medura products and treatment options that may align with your health goals.

Start Quiz

Educational only. Not medical advice.