Product image is for illustrative purposes only. Actual medication, packaging, and labeling may vary depending on the dispensing pharmacy.
Enclomiphene Capsule
Enclomiphene is an oral capsule that encourages the body to produce more of its own testosterone, rather than replacing it. It is compounded and not FDA-approved, so a provider reviews whether it's appropriate for you. The quantity is set by your prescription.
- Lab-informed decisions
- Several formulation options
- Ongoing follow-up
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How it works
Submit your free assessment
Step 1: Complete your medical assessment for review by a licensed medical provider. If appropriate, the provider will determine whether the treatment is right for you.
Get your plan and your order at home
Step 2: If appropriate, your provider selects a formulation, dose, and schedule based on your labs and goals. Your order ships in plain, unbranded packaging.
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Step 3: Access your patient portal to communicate with your care team, ask questions, and get support throughout your treatment journey.
Enclomiphene Capsule
How Enclomiphene supports healthy testosterone care
Enclomiphene Citrate is an oral capsule offered in two strengths, 25 mg and 51 mg. It is a different medication from testosterone and is not interchangeable with testosterone injections or cream. Testosterone therapy is not one-size-fits-all. Your provider uses your symptoms, history, and lab results to decide whether treatment fits and which formulation makes sense.
Lab-informed decisions
Your provider reviews existing labs or orders new ones to confirm whether low testosterone is present before recommending anything.
Several formulation options
Injectable, topical, and oral options are available through our pharmacy network. Your provider explains why one may suit you better than another.
Ongoing follow-up
Your provider checks in on how you are responding and adjusts your plan over time rather than writing a single prescription and moving on.
Provider-guided from start to finish
A licensed provider reviews your health history, checks for contraindications, sets an appropriate starting plan, and monitors your progress over time.
How to use it
Clear instructions for your specific formulation arrive with your first order.
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Your health deserves more than a one-size-fits-all approach.
Medura connects you with licensed medical professionals who take the time to review your health history, evaluate your individual needs, and determine which treatments may be right for you.
We believe quality healthcare should come with professional oversight, personalized attention, and honest, transparent medication pricing.
No unnecessary medication markups. No confusing treatment pricing. Just a more straightforward approach to getting the care you deserve.
Licensed Medical Professionals
Your treatment is evaluated by qualified, licensed providers.
Personalized Medical Evaluations
Recommendations are based on your individual health needs.
Provider-Approved Prescriptions
Medication is prescribed only when clinically appropriate.
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Connect with a licensed medical professional and discover whether treatment is right for you. Prescriptions require a medical evaluation and provider approval.
Quality and ingredient standards
Made in the U.S.A.
Some treatments are compounded by licensed U.S. pharmacies in facilities registered with the FDA. Registration does not mean a compounded medication is an FDA-approved finished medication.
USP <797>
Sterile compounding standards.
Documented handling.
Every batch released to spec.
ISO Class 7
Cleanroom-grade air.
Filtered environments.
Tighter contamination control.
Clean ingredients, careful delivery
- No heavy metals
- No added dyes
- Licensed U.S. pharmacies
- Provider-prescribed
- Cold-chain protection
- Plain, unbranded packaging
- Serves all 50 states
- HSA and FSA eligible
Medication guide
What to know about Enclomiphene Capsule
General education to help you prepare for a conversation with a licensed provider. It is not a prescription or personal medical advice.
- Generic name
- Enclomiphene citrate
- Drug class
- Selective estrogen receptor modulator (SERM)
- Form
- Capsule taken by mouth
- Regulatory status
- Not FDA-approved for any use
Enclomiphene is not FDA-approved for any use. It is one of the two components of clomiphene citrate (Clomid), which is FDA-approved for ovulation problems in women. Enclomiphene capsules are compounded, and their quality and consistency have not been reviewed by FDA.
Compounded medications are not FDA-approved. FDA does not review them for safety, effectiveness or quality before they are dispensed. A compounded preparation can differ from approved products in strength, ingredients, dosage form and how it is absorbed, so it should not be assumed to work the same way as an approved medication. Compounding is meant for patients whose needs cannot be met by an FDA-approved drug.
Overview
Enclomiphene is used in some men with low testosterone, especially those who want to preserve fertility, to prompt the body to make more of its own testosterone.
Who may be evaluated for it
- Men with low testosterone caused by low brain signals (secondary hypogonadism) who want to maintain sperm production.
Who may not be a good fit
- Men with primary testicular failure (the testicles cannot respond to stronger signals).
- Men with a history of blood clots, liver disease or visual problems with similar medicines.
- Women who are pregnant.
How it works
Estrogen normally tells the brain to slow down the hormones that drive testosterone production. Enclomiphene blocks estrogen receptors in the brain, so the pituitary releases more LH and FSH. The testicles then make more testosterone and sperm.
Potential benefits and realistic timelines
What the evidence supports
- Clinical trials submitted for approval showed enclomiphene raised testosterone while maintaining sperm counts, unlike testosterone injections or gel.
Not established
- Long-term safety, and whether higher testosterone from enclomiphene improves symptoms as much as testosterone therapy.
- FDA did not approve it, and data on compounded products is lacking.
- 2 to 6 weeksTestosterone levels usually rise within several weeks.
- About 3 monthsSymptoms and sperm production are typically reassessed.
Results vary from person to person. Your provider decides whether and how long to continue.
How it’s used
- Taken by mouth on the schedule your provider sets, at about the same time of day.
If you miss a dose
Take it when you remember the same day; otherwise skip it. Do not double up.
Storage and handling
Room temperature in a closed container.
Your prescription label and provider instructions always take priority over this general information. Do not change your dose or stop without talking to your provider.
Side effects and safety
More common, usually manageable
- Headache
- Hot flashes
- Nausea
- Mood changes or irritability
Less common but serious
- Visual disturbances such as blurring or spots (reported with clomiphene)
- Blood clots
- High red blood cell count
Get medical help right away
- Any vision change: stop and contact your provider
- Leg swelling and pain, or sudden chest pain or breathlessness
Call 911 or go to the nearest emergency room for chest pain, trouble breathing, swelling of the face or throat, fainting, or signs of a stroke (sudden weakness, numbness, trouble speaking or seeing).
Pregnancy, breastfeeding and fertility
Not for use in pregnancy. In men, it is used partly because it tends to preserve sperm production.
Interactions and combinations
Known interactions
- Avoid combining with other estrogen modulators (such as clomiphene or tamoxifen) unless directed.
Related treatments and options
Listed for education, not as a recommendation to combine. Any combination needs your provider’s approval.
- Testosterone therapyEvidence insufficient
Combining is uncommon and not well studied.
- Anastrozole SREvidence insufficient
Evidence is limited.
Monitoring and follow-up
- Testosterone, LH, FSH and estradiol at baseline and after a few weeks.
- Hematocrit and liver tests periodically.
- Semen analysis if fertility is a goal.
Lab tests and follow-up visits are not included in the medication price unless your plan says so. Your provider will tell you what is needed.
Alternatives to discuss
- HCG (Chorionic)
FDA-approved for male hypogonadotropic hypogonadism; injected.
- Testosterone Cypionate
FDA-approved testosterone replacement, but it suppresses sperm production.
- Clomiphene citrate
FDA-approved for women; used off-label in men by some specialists.
Lab tested medications for quality and potency.
Every medication ships from a licensed U.S. pharmacy in our network, delivered straight to your door.
Third party quality control testing
Compounded in U.S. pharmacies
Dosage, Schedule & Supply
- Dosage
- 25 mg or 51 mg.
- Schedule
- Determined by your prescribing provider.
- Supply
- Quantity set by your prescription.
- Estimated Supply Duration
- Varies based on the quantity and schedule on your prescription.
Supply duration is an estimate based on the prescribed treatment plan. Actual duration may vary depending on dosage, frequency of use, and medication expiration.
Treatment information is for educational purposes. Your licensed healthcare provider will determine the appropriate dosage and schedule. Always follow your prescription instructions.
Frequently Asked Questions
Is enclomiphene FDA-approved?
No. It was studied for male hypogonadism but has not been approved.
How is it different from testosterone?
Testosterone replaces the hormone and usually suppresses sperm. Enclomiphene prompts your body to make its own, which tends to preserve sperm.
What if my vision changes?
Stop taking it and contact your provider promptly.
Do I need a prescription?
Yes. After your free consultation, a licensed provider reviews your intake and relevant lab work to decide whether testosterone therapy is appropriate for you.
Will I need lab work?
Your provider will review existing labs or order new ones to confirm whether low testosterone is present before recommending treatment.
What if a provider decides this isn’t right for me?
Your consultation is free. If a provider decides testosterone therapy isn’t appropriate for you, they will explain why and may suggest other options.
Can I use my HSA or FSA?
Yes. Medura accepts HSA and FSA cards at checkout, and we can provide documentation for reimbursement if you need it.
How is it shipped?
Your treatment arrives in plain, unbranded packaging with no pharmacy name on the outside. Temperature-sensitive items ship with cold-chain protection.
What happens after I request treatment through Medura?
You complete an online assessment about your health history, current medications and goals. A licensed provider reviews it and decides whether a prescription is appropriate. Completing the assessment does not guarantee a prescription. If one is written, a licensed pharmacy prepares and ships it, and your provider can adjust or stop treatment as needed. If lab work is needed, your provider will tell you; it may be ordered and billed separately.
What to expect and possible side effects
- 1
Start with a consultation and labs
A licensed provider reviews your intake and health history, and orders or reviews lab work to confirm whether low testosterone is present before recommending treatment.
- 2
A plan matched to your labs
If appropriate, your provider selects a formulation, dose, and schedule based on your lab results and goals, and explains how to use it.
- 3
Ongoing monitoring
Your provider follows up to check how you are responding and adjusts your plan as needed over time.
Questions to ask your provider
- 1.Is my low testosterone the type that responds to enclomiphene?
- 2.What are the risks of using a non-approved medication?
- 3.Which labs will you check, and when?
- 4.How does it compare with hCG for my fertility goals?
References
- Compounding and the FDA: Questions and Answers (FDA)(opens in a new tab)
- Bulk Drug Substances Used in Compounding Under Section 503A (FDA)(opens in a new tab)
- Clomiphene/enclomiphene background (MedlinePlus: Clomiphene)(opens in a new tab)
Sources last checked October 17, 2026. This page is for general education and does not replace advice from a licensed provider. Treatment requires a clinical evaluation, and a prescription is written only if a provider decides it is appropriate. Individual results vary.
Related Products & Treatments
Explore other options that may support your goals.
Testosterone Cypionate InjectableCommercial injectable testosterone, 10 mL vial. Helps with symptoms of low testosterone such as low energy, low drive and lost muscle.View details for Testosterone Cypionate Injectable
Testosterone CreamTopical testosterone in a 30 g cream. Helps with symptoms of low testosterone such as low energy, low drive and lost muscle.View details for Testosterone Cream
hCG InjectableAn injectable HCG kit, a separate medication. Helps maintain testicular function and fertility during testosterone therapy.View details for hCG Injectable
Anastrozole SR CapsuleA sustained-release aromatase inhibitor capsule, titrated per prescription. Helps keep estrogen in balance for patients on testosterone therapy.View details for Anastrozole SR Capsule
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