Medura GHK-Cu Cream pump bottle in premium metallic navy packaging

Product image is for illustrative purposes only. Actual medication, packaging, and labeling may vary depending on the dispensing pharmacy.

Skincare

GHK-Cu Cream

GHK-Cu is a copper peptide found naturally in the skin and prized in skincare for its role in renewal. This 0.5% compounded cream brings it into an easy topical routine, though evidence for visible results is still modest. Supplied in 30 g containers, with the number set by your prescription.

  • Prescription-strength options
  • Strength matched to you
  • Adjustments as you go

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How it works

  1. Submit your free assessment

    Step 1: Complete your medical assessment for review by a licensed medical provider. If appropriate, the provider will determine whether the treatment is right for you.

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  2. Get your plan and your order at home

    Step 2: If approved, your provider selects a formulation and strength and explains how to introduce it into your routine. Your order ships in plain, unbranded packaging.

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  3. Receive 24/7 Support and Ongoing Care

    Step 3: Access your patient portal to communicate with your care team, ask questions, and get support throughout your treatment journey.

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GHK-Cu Cream

How GHK-Cu supports clearer-looking skin

GHK-Cu Cream 0.5% is a topical cream containing the copper peptide GHK-Cu. It is supplied in 30 g containers. Prescription formulations are stronger than what you find on a store shelf, so the right choice depends on your skin type, history, and goals. A licensed provider helps you pick.

  • Prescription-strength options

    Tretinoin cream and gel, plus compounded creams like Cashmere Cream and GHK-Cu Cream, are available through our pharmacy network.

  • Strength matched to you

    Your provider selects a formulation and strength and explains how to introduce it into your routine at a comfortable pace.

  • Adjustments as you go

    Skin changes over time. Your provider is available to adjust your plan as your skin responds.

  • Provider-guided from start to finish

    A licensed provider reviews your health history, checks for contraindications, sets an appropriate starting plan, and monitors your progress over time.

  • How to use it

    Clear application instructions for your specific formulation arrive with your first order.

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Quality and ingredient standards

Made in the U.S.A.

Some treatments are compounded by licensed U.S. pharmacies in facilities registered with the FDA. Registration does not mean a compounded medication is an FDA-approved finished medication.

  • USP <797>

    Sterile compounding standards.

    Documented handling.

    Every batch released to spec.

  • ISO Class 7

    Cleanroom-grade air.

    Filtered environments.

    Tighter contamination control.

Clean ingredients, careful delivery

  • No heavy metals
  • No added dyes
  • Licensed U.S. pharmacies
  • Provider-prescribed
  • Cold-chain protection
  • Plain, unbranded packaging
  • Serves all 50 states
  • HSA and FSA eligible

Medication guide

What to know about GHK-Cu Cream

General education to help you prepare for a conversation with a licensed provider. It is not a prescription or personal medical advice.

Generic name
Copper tripeptide-1 (GHK-Cu)
Drug class
Copper peptide
Form
0.5% cream
Regulatory status
Not FDA-approved for any use

GHK-Cu is not an FDA-approved drug for any use. It is used mainly as a cosmetic ingredient. This is a compounded cream whose safety and effectiveness have not been reviewed by FDA.

Compounded medications are not FDA-approved. FDA does not review them for safety, effectiveness or quality before they are dispensed. A compounded preparation can differ from approved products in strength, ingredients, dosage form and how it is absorbed, so it should not be assumed to work the same way as an approved medication. Compounding is meant for patients whose needs cannot be met by an FDA-approved drug.

Overview

GHK-Cu cream is used for skin texture and the appearance of fine lines. Evidence is limited.

Who may be evaluated for it

  • Adults interested in a non-retinoid option for skin texture, who understand the evidence is limited.

Who may not be a good fit

  • People with a copper allergy or Wilson disease.
  • People with broken or infected skin in the treatment area.
  • People who are pregnant should ask first (not studied).

How it works

GHK is a small peptide found naturally in the body that binds copper. Lab studies suggest it may signal skin cells to make collagen and support wound repair.

What is still uncertain

Most evidence comes from lab and small cosmetic studies. How much penetrates the skin and what it does in people is not well established.

Potential benefits and realistic timelines

No clinical benefit has been established in well-designed human trials for this use.

Early or limited research

  • Small, mostly industry-funded cosmetic studies report improvements in fine lines and skin density.

Not established

  • Effectiveness in well-designed clinical trials.
  • Benefits for hair growth or wound healing in patients.
  1. About 8 to 12 weeksSmall cosmetic studies assessed results over this period. Individual results vary.

Results vary from person to person. Your provider decides whether and how long to continue.

How it’s used

  • Apply a thin layer to clean skin as directed, usually once or twice daily.

If you miss a dose

Apply at the next usual time.

Storage and handling

Room temperature, closed, away from light.

Your prescription label and provider instructions always take priority over this general information. Do not change your dose or stop without talking to your provider.

Side effects and safety

More common, usually manageable

  • Mild redness or irritation
  • Blue-green tint on skin or fabric if overapplied

Less common but serious

  • Allergic contact dermatitis

Get medical help right away

  • Swelling of the face or trouble breathing

Call 911 or go to the nearest emergency room for chest pain, trouble breathing, swelling of the face or throat, fainting, or signs of a stroke (sudden weakness, numbness, trouble speaking or seeing).

Pregnancy, breastfeeding and fertility

Not studied in pregnancy or breastfeeding; ask your provider.

Interactions and combinations

Known interactions

  • Vitamin C (ascorbic acid) and strong acids may degrade copper peptides if applied at the same time.

Related treatments and options

Listed for education, not as a recommendation to combine. Any combination needs your provider’s approval.

  • TretinoinEvidence insufficient

    Often layered, but no evidence of added benefit; apply at different times if irritated.

Monitoring and follow-up

  • Skin review after about 3 months.

Lab tests and follow-up visits are not included in the medication price unless your plan says so. Your provider will tell you what is needed.

Alternatives to discuss

Potency TestTested
Sterility TestTested
Endotoxin TestTested
pH TestTested

Lab tested medications for quality and potency.

Every medication ships from a licensed U.S. pharmacy in our network, delivered straight to your door.

  • Third party quality control testing

  • Compounded in U.S. pharmacies

Dosage, Schedule & Supply

Dosage
0.5% concentration.
Schedule
Determined by your prescribing provider.
Supply
30 g containers. The number per supply is set by your prescription.
Estimated Supply Duration
Varies based on the amount applied and how often it is used.

Supply duration is an estimate based on the prescribed treatment plan. Actual duration may vary depending on dosage, frequency of use, and medication expiration.

Treatment information is for educational purposes. Your licensed healthcare provider will determine the appropriate dosage and schedule. Always follow your prescription instructions.

Frequently Asked Questions

Is GHK-Cu proven to work?

Evidence is limited to lab work and small cosmetic studies. It is not an FDA-approved drug.

Can I use it with tretinoin?

Some people do. There is no evidence of extra benefit. Ask your provider.

Do I need a prescription?

Yes, for tretinoin and compounded formulations. After your free consultation, a licensed provider reviews your skin history to decide what’s appropriate for you.

How is it shipped?

Your treatment arrives in plain, unbranded packaging with no pharmacy name on the outside.

Can I use my HSA or FSA?

Yes. Medura accepts HSA and FSA cards at checkout, and we can provide documentation for reimbursement if you need it.

What happens after I request treatment through Medura?

You complete an online assessment about your health history, current medications and goals. A licensed provider reviews it and decides whether a prescription is appropriate. Completing the assessment does not guarantee a prescription. If one is written, a licensed pharmacy prepares and ships it, and your provider can adjust or stop treatment as needed. If lab work is needed, your provider will tell you; it may be ordered and billed separately.

What to expect and possible side effects

  1. 1

    Start with a consultation

    A licensed provider reviews your intake, skin history, and goals to determine whether a prescription formulation is appropriate.

  2. 2

    A routine built for your skin

    If approved, your provider selects a formulation and strength and explains how to introduce it into your routine.

  3. 3

    Follow-up as needed

    Your provider is available to adjust your plan as your skin responds.

Questions to ask your provider

  1. 1.Would tretinoin give me better-proven results?
  2. 2.How long should I try it?
  3. 3.Can I use it with my current products?

References

Sources last checked October 17, 2026. This page is for general education and does not replace advice from a licensed provider. Treatment requires a clinical evaluation, and a prescription is written only if a provider decides it is appropriate. Individual results vary.

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