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“I have my best sleep when taking Cloud Nine Syrup.!”
Herbal Syrup
4.9 (2441 reviews)Nine fermented herbs and 5 mg of melatonin in a smooth nighttime syrup.
Herbal Nighttime Syrup brings our concentrated extract of nine fermented herbs together with 5 mg of melatonin in a smooth liquid. It suits anyone who would rather take a spoonful than swallow a capsule or chew a gummy. Make it part of a consistent evening routine.
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Product Details
- Nighttime · Unflavored
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Our Herbal Extract Meets Melatonin, by the Spoonful
This syrup brings our highly concentrated extract of nine fermented herbs together with added melatonin in a smooth liquid. It is the same nighttime formulation concept as the Nighttime Gummies, in a format for people who prefer a spoonful to a chew.


Lemon Balm
The calming citrus herb
Some human researchA bright, lemon-scented member of the mint family, lemon balm has been steeped in teas and tonics for centuries. It is traditionally used to help you feel calm, settled, and at ease.
What the research says: Small, short studies have linked lemon balm extracts to greater self-reported calmness and mood, and it has been studied alongside valerian for restlessness at bedtime. Studies are small and doses vary.

Skullcap
A classic herb for a quiet mind
Limited human researchAmerican skullcap is a long-standing staple of herbal practice, traditionally used to ease everyday tension and support a relaxed, steady mind.
What the research says: The evidence is thin. A small study in healthy adults reported mood improvements, but there are very few trials. Most of what is known comes from traditional use.

Kava Kava
The root made for unwinding
Some human researchPacific Islanders have prepared kava root for generations as a shared, relaxing drink. It is traditionally used to promote a sense of calm and ease at the end of the day.
What the research says: Kava is the best studied herb in the blend. Several clinical trials, summarized in a Cochrane review, found short-term improvements in anxiety. Rare cases of liver injury have been reported with kava products, so it is not for people with liver conditions or who drink alcohol regularly.

Holy Basil
Tulsi, the adaptogenic favorite
Limited human researchRevered in Ayurveda as tulsi, holy basil is traditionally used to support the body’s response to everyday stress and promote a feeling of balance.
What the research says: A few small trials of holy basil extracts reported lower self-rated stress and anxiety scores. The studies are small and vary in quality, so the results are promising but not settled.

Passion Flower
Soft, floral, and soothing
Some human researchWith its striking blooms, passion flower is traditionally used to quiet a busy mind and support restful, relaxed evenings.
What the research says: Small trials have looked at passion flower for anxiety, and a one-week study of passion flower tea found better self-reported sleep quality. The results are encouraging but come from small studies.

Catnip
A gentle mint-family herb
Traditional useBest known for cats, catnip has also long been steeped by people as a mild, soothing tea to help settle the body and unwind.
What the research says: People have long steeped catnip as a mild, calming tea. Lab and animal studies exist, but we are not aware of strong human trials, so we describe its role as traditional.

Wild Lettuce
A traditional evening herb
Traditional useWild lettuce has a long history in folk herbalism as a calming herb, traditionally used to support relaxation and a peaceful wind-down.
What the research says: What is known comes mostly from folk use and animal studies. We are not aware of solid human trials, so we describe it as traditional only.

Damiana
The aromatic herb of Central America
Traditional usePrized for its warm, floral aroma, damiana is traditionally used to support a positive mood and an uplifted sense of well-being.
What the research says: Damiana has been studied mainly in lab and animal settings, with very little research in people. Its place in the blend rests on traditional use.

White Willow Bark
A time-honored bark
Some human researchUsed for centuries across herbal traditions, white willow bark is traditionally relied on to support everyday physical comfort.
What the research says: The bark contains salicin, a relative of the compound in aspirin. Trials of standardized extracts have looked at low-back pain and osteoarthritis, with the best support for low-back pain. People who are sensitive to aspirin or take blood thinners should check with a clinician first.

Melatonin
5 mg per bottle
Well studiedMelatonin is the hormone your body makes naturally to signal that it is time for bed. Each bottle of Nighttime Syrup contains 5 mg, added to the nine herbs to support your natural sleep cycle.
What the research says: Reviews of clinical trials find that melatonin modestly shortens the time it takes to fall asleep, and it is well established for shifting sleep timing, as with jet lag. It is not a sedative, and the effects are modest.
Nine fermented herbs and melatonin, in a nighttime format you can pour.
What to Expect From the Nighttime Syrup
Taken by the spoonful in the evening, the syrup pairs the herbal blend with added melatonin to support your nighttime routine. We do not promise specific sleep outcomes.
- Some human research
A calmer evening
Lemon balm and passion flower have small human studies on calmness, and passion flower tea was linked to better self-reported sleep quality in one small study. The evidence is encouraging, not settled.
- Well studied
Melatonin for your routine
Melatonin is the hormone your body makes naturally to signal bedtime. Trials find it modestly shortens the time it takes to fall asleep. It is not a sedative.
Gummies or syrup, your choice
The Nighttime Gummies and Nighttime Syrup share the same formulation concept. Choose the chew or the spoonful based on what you prefer to take. Compare serving and melatonin amounts on each label.
No pills to swallow
A liquid is a simple option for anyone who prefers not to swallow capsules, and it is easy to take at the same time each evening.
How we describe the evidence
- Well studied
- Supported by multiple clinical trials or reviews.
- Some human research
- Small or early human studies point in a positive direction.
- Limited human research
- Little human research. Findings are preliminary.
- Traditional use
- Based on long-standing use, not on clinical trials.
Research findings come from studies of specific extracts, doses, and groups of people and may not apply to this product. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Frequently Asked Questions
What is in Herbal Nighttime Syrup?
Herbal Nighttime Syrup is built around the Medura nine-herb blend: lemon balm, skullcap, kava kava, holy basil, passion flower, catnip, wild lettuce, damiana, and white willow bark. The full ingredient and Supplement Facts panel is printed on the product label.
How much melatonin is in the syrup?
Each bottle of Nighttime Syrup contains 5 mg of melatonin, added to the nine herbs.
Is melatonin a sedative?
No. Melatonin is the hormone your body makes naturally to signal bedtime. Trials find it modestly shortens the time it takes to fall asleep, and the effects are modest.
Who should check with a clinician first?
Anyone who is pregnant or nursing, takes medication, or has a health condition. Kava is not for people with liver conditions or who drink alcohol regularly, and people sensitive to aspirin or on blood thinners should ask about white willow bark.
What if it is not right for me?
Medura backs every over-the-counter purchase with a 90-day guarantee. Reach out to support@medurahealth.com and we will help.
Customer Reviews
- Christopher T.Verified BuyerWas this helpful?
I back these products 110%!!
Brittany W.Verified BuyerWas this helpful?... this syrup actually works. i wish it was in a bigger bottle so i can take it every day but a girl gotta ration it out. absolutely love this product.
June T.Verified BuyerWas this helpful?Love this product helps so much with my sleep
ValerieVerified BuyerWas this helpful?Every flavor I’ve tríed has been on point.
Mark S.Verified BuyerWas this helpful?This is a wonderful product for anxiety and pain. I'm actually able to sleep at night after taking this product. Can't wait to order more!
Donna H.Verified BuyerWas this helpful?
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